Use in Pregnancy: There is very limited data from the use of diltiazem in pregnant patients. Diltiazem has been observed to induce increased fetal mortality and malformations in certain animal species. Diltiazem is therefore not recommended during pregnancy, as well as in women of childbearing potential not using effective contraception.
Use in Lactation: Diltiazem is excreted in breastmilk. Women should not breastfeed while on diltiazem treatment. If use of diltiazem is considered medically essential, breastfeeding should be terminated.